Project: Defining the placental response to SARS-CoV-2 infection
Subbarao Group
In this project we will investigate SARS-CoV-2 infection of placental cells using an in vitro induced trophoblast stem cell model. We will compare virus replication and host responses to other important teratogenic viruses such as Zika Virus and cytomegaloviruses. We will also obtain human placental tissue to establish explant and organoid models to further explore the effects of SARS-CoV-2 infection.
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Subbarao Group
4 vacancies
Research in the Subbarao laboratory focuses on respiratory viral diseases of global importance including pandemic and seasonal influenza and coronaviruses including SARS-CoV-2 (COVID-19) and human coronaviruses. We study virus biology and pathogenesis, airborne spread of respiratory viruses, immune responses to infection and vaccination, and antiviral drugs. We use state of the art techniques in virology, molecular biology and immunology, including reverse genetics, infection of stem cell derived tissues and studies in animal models.
Subbarao Group Current Projects
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Defining the placental response to SARS-CoV-2 infection
PhD/MPhil, Master of Biomedical Science
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Studying virus-host interactions using complex in vitro respiratory culture systems
PhD/MPhil, Master of Biomedical Science, Honours
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Defining the role of secreted mucins in seasonal human coronavirus infection
Master of Biomedical Science, Honours
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Understanding how SARS-CoV-2 Spike antigen leads to myocarditis
Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.