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Staff

Dr Lauren Holz

Post-doctoral Researcher

Overview

Dr Holz is a liver immunologist who completed her PhD at the University of Sydney where she identified novel CD8+ T cell tolerance pathways utilised by the murine liver. After undertaking post-doctoral studies on hepatitis infected patients at NIH she returned to Australia in 2015. Since this time she has performed key studies vital to the identification of liver tissue-resident memory T cells and identified the factors necessary for Trm cells to seed the liver. Building on this critical data she began developing novel vaccine strategies to target the liver stage of malaria. In the past four years she has developed and patented two novel vaccine platforms, the most recent of which is an mRNA vaccine.

Publications

Selected publications

Glycolipid-peptide vaccination induces liver-resident memory CD8 + T cells that protect against rodent malaria
2025 · journal-article
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Development of Plasmodium-specific liver resident-memory CD8+ T cells after heat-killed sporozoite immunization in mice.
2025 · journal-article
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Harnessing liver-resident memory T cells for protection against malaria.
2025 · journal-article
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