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Staff

Dr Carolien van de Sandt

Senior Research Fellow

Overview

Dr Carolien van de Sandt completed her PhD in 2016 at the Erasmus University in Rotterdam (Netherlands) where she investigated the longevity, cross-reactivity and immune evasion strategies of influenza-specific CD8+ T-cells, followed by two years of postdoctoral research. In 2018, she joined the Kedzierska Laboratory as a MSCA Research Fellow to study the mechanisms that underly gain-and-loss-of CD8+ T-cell function across the human lifespan. In 2020, she temporally relocated to Sanquin Research (Netherlands) to study SARS-CoV-2 immunity in autoimmune patients, where she still holds an honorary position. In 2022 she was awarded the ARC-DECRA fellowship to continue her Aging Immunity and T-Cell Development research at the Doherty Institute (University of Melbourne).

Publications

Selected publications

Central memory T cells with key TCR repertoires and gene expression profiles dominate influenza CD8+ T cell pools across the human lifespan.
2025 · journal-article
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A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells.
2025 · journal-article
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Gradual changes within long-lived influenza virus-specific CD8<sup>+</sup> T cells are associated with the loss of public TCR clonotypes in older adults.
2025 · journal-article
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