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Staff

Associate Professor Adam Wheatley

Laboratory Head

Overview

After a PhD at University of Melbourne, Associate Professor Wheatley undertook postdoctoral training at the Vaccine Research Center, NIH, USA. There he focused upon defining correlates of immune protection following clinical immunisation trials and characterising humoral immunity elicited to experimental HIV and influenza vaccines. He returned to the University of Melbourne in 2015, where he established a team focused upon understanding mechanisms to generate broad and lasting antibody-based protection against viral diseases such as influenza and SARS-CoV-2. Specific interests include the control of B cell trafficking, germinal centre and memory formation, the basis for cross-reactive recognition of antigenically diverse pathogens by antibody, and the rational design and pre-clinical testing of novel vaccine concepts.

Publications

Selected publications

Defining B cell immunodominance to viruses
2025 · journal-article
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H5N1 Vaccine–Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem
2025 · journal-article
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Deconvoluting TCR-dependent and -independent activation is vital for reliable Ag-specific CD4 + T cell characterization by AIM assay
2025 · journal-article
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