Development of autoimmune diseases has been linked to disturbances in the microbes that normally colonise our body surfaces. However, precisely how these microorganisms and the resulting stimulation of the immune system impact on T cells still remains elusive. Building on extensive preliminary data available in the lab, this project investigates how the microbiota influences particular cytokine responses that are highly relevant to our understanding of T cell-mediated autoimmune disease, such as type I diabetes.
Public Health
