Dr Thomas Rasmussen is a Clinical Research Fellow in Professor Sharon Lewin’s laboratory. Thomas has a Doctor of Medicine degree from Aarhus University, Denmark in 2006 and has since been involved in clinical infectious disease medicine and HIV-related science with research activities primarily including clinical, translational and epidemiological studies. He completed his PhD in HIV in 2014, which was focused on the clinical use of histone deacetylase inhibitors to reverse HIV-1 latency. Thomas’ ongoing research is focused at understanding the barriers to curing HIV-1 infection and testing new strategies aimed at eliminating latent HIV-1 infection.
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Key Achievements
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Based at Aarhus University Hospital, Denmark, Thomas has led a pre-clinical study of histone deacetylase inhibitors and their potential use in HIV-1 infection. Subsequently, he was the principal investigator on a phase I/IIa clinical trial investigating the effect of the histone deacetylase inhibitor, panobinostat, on HIV-1 latency in patients with chronic HIV-1 infection. The primary results of this study, which was funded by a grant from The Danish Research Council, were published in The Lancet HIV in October, 2014. He is also an investigator on several on-going clinical studies investigating interventions aimed at the development of a cure for HIV.
Publications
Research Groups
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Lewin Group
The focus of the Lewin group is to understand why HIV infection persists on antiretroviral therapy and to develop new strategies to eliminate latency. The lab also researches factors that drive liver disease in HIV-hepatitis B virus co-infection. The lab is also actively involved in COVID in relation to pathogenesis, the use of primary tissue models, and developing therapeutics using gene editing strategies.
Lab Team
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Director - The Peter Doherty Institute for Infection and Immunity
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Deputy Head Lewin Lab | Senior Research Fellow
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Dr Wei Zhao
Research Fellow
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Dr Chris Chiu
Research Fellow
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Dr Youry Kim
Research Fellow
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Dr Stan Kan
Research Fellow
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Postdoctoral Research Fellow
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Clinical Research Liason Officer
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Dr Judy Chang
Research Systems Administrator
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Infectious Diseases Physician
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Carolin Tumpach
Research Support Officer
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Rosalyn Cao
Research Support Officer
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Danielle Fong
Research Support Officer
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Abigail Tan
Research Support Officer
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Jared Stern
PhD Candidate
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Rachel Pascoe
PhD Candidate
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Haoming Liu
PhD Candidate
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Kiho Tanaka
PhD Candidate
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Rory Shepherd
PhD Candidate
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Lauren Wallace
Honours Student
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Bridget Fisher
Honours Student
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Associate Professor Edwina Wright
Clinical Affiliate
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Dr James McMahon
Clinical Affiliate
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Head, Clinical Virology and HIV Services, Deputy Director Department of Infectious Diseases Austin Health
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Associate Clinical Director of HIV Cure Studies
Full University of Melbourne profile