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Dr Sidonia Eckle

Dr Sidonia Eckle graduated with a Bachelor of Science in Biochemistry from the Technical University of Munich in 2006, with a Masters of Science in Molecular Cell Biology from Uppsala University and the Karolinska Institute in 2007, and with a PhD in Immunology under Professor James McCluskey from the University of Melbourne in 2013. Upon completion of her PhD, Sidonia continued in James’ laboratory as a postdoctoral researcher. In 2014 and 2015, Sidonia was also an intern in the University of Melbourne’s Commercial department as part of the ‘Molecules to Medicine’ professional development program for biomedical early career scientists, sponsored by the Victorian government. Sidonia organises monthly MAIT cell workshops involving laboratories at the University of Melbourne and Monash University.

  • Key Achievements
    • In James’ laboratory, Sidonia played a pivotal role in identifying the activating ligands of MAIT cells, a recent major breakthrough in the field. She was subsequently joint first author in a Nature paper in 2014. Capitalising on this knowledge, Sidonia generated tetramers (MR1-tetramers), which specifically identify MAIT cells. In 2014, Sidonia was awarded a career development award by the Victorian Infection and Immunity Network and received an Early Career Research grant from the University of Melbourne.

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    Research Groups
    • McCluskey Group

      MAIT cells respond to precursors of riboflavin, allowing the immune system to detect microbial invaders. The McCluskey group aims to understand their role in infection/inflammatory conditions and is tackling this question using mouse models, human tissue analysis and structural biology.

      If you are interested to collaborate with us, please, feel free to get in touch. Please note that the human and mouse MR1 tetramers developed in our laboratory can now be ordered through the NIH tetramer core facility.

      Lab Team

      McCluskey Group

      • ARC Future Fellow
      • Senior Research Officer
      • Trust postdoctoral fellow
      • ARC DECRA Research Fellow
      • Criselle D'souza
        PhD Student
      • Lyudmila Kostenko
        Research Assistant
      • Bronwyn Meehan
        Research Assistant
      • Michael Souter
        Honours Student
      • Lars Kjer-Nielsen
        Research Officer
      • Bonnie van Wilgenburg
        Visiting Research Officer
      • Troi Pediongco
        Research Assistant
      • Freya Harewood
        PhD Student
      • Huimeng Wang
        PhD Student
      • Michael Souter
        PhD Student
      • Shihan (Tony) Li
        PhD Student
      • Xin Yi Lim
        Honours Student
      • Mai Shi
        Masters Student
      • Robyn Esterbauer
        Honours Student

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