The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

People

Dr Sarah Londrigan

Dr Sarah Londrigan

Dr Sarah Londrigan

(03) 9035 3481 | sarahll@unimelb.edu.au

Position:
Senior Research Fellow
Theme(s):
Immunology, Viral Infectious Diseases, Host Pathogens Interactions , Influenza
Discipline(s):
Discovery Research
Unit(s):
Department of Microbiology and Immunology (DMI)
Lab Group(s):
Brooks Group, Reading Group

Dr Sarah Londrigan completed her Bachelor of Science (Honours) and PhD research at the University of Melbourne in 2002, where she identified novel cell surface receptors for rotavirus entry during infection of host cells. Sarah’s postdoctoral research from 2002 to 2008 at the Walter and Eliza Hall Institute (WEHI) involved creating immunomodulatory adenoviruses that generated local immunosuppression during islet transplantation to treat Type I diabetes. Since then, her research has focused on pathways that influenza, and other respiratory viruses, use to infect host cells.  Specifically, she is investigating how airway immune cells control viral replication to prevent severe infection.  Current projects include investigating why particular respiratory viruses are highly pathogenic, leading to very severe disease.

  • Key Achievements
    • During her postdoctoral training, Sarah was awarded a Juvenile Diabetes Research Foundation Fellowship. Upon her return to the University of Melbourne, Sarah was the recipient of a Melbourne Research Fellowship and an Early Career Research Award. Since 2008, she has received continual grant support from the NHMRC, including a current Ideas Grant to investigate how macrophages regulate influenza virus infection (2020-2022), as well as funding through several industry contracts. Sarah is involved in research related activities relating to virology, immunology and women in science through her roles in the Immunology Group of Victoria (IgV), the Women in Science Parkville Precinct (WiSPP) group and The Australasian Virology Society.

    Publications
    Loading ORCID data...
    Research Groups
    • Brooks Group

      Research in Andrew’s laboratory is largely centred on how natural killer cells and T cells impact the outcomes of viral infection, cancer and transplantation.


      Lab Team

      Brooks Group

      • Dr Lucy Sullivan
        Senior Research Fellow
      • Dr Jie Lin
        Research Officer
      • Dr Philippa Saunders
        Research Officer
      • Dr Sanda Stankovic
        Research Officer
      • Jacqueline Widjaja
        Research Assistant
      • Christopher Harpur
        PhD Student
      • Shu Cheng Wong
        PhD Student
      • Dr Shinta Dewi
        PhD Student
      • Senior Research Fellow
    • Reading Group

      Patrick’s group investigates how the body first detects and responds to respiratory viruses. They investigate viral attachment factors, cellular receptors and entry pathways, virus-induced activation of host genes and the mechanisms by which intracellular host proteins can block virus replication.


      Lab Team

      Reading Group

      • Tina Meischel
        PhD student
      • Melkamu Tessema
        PhD student
      • Senior Research Fellow
      • Lara Schwab
        PhD student
      • Harry Stannard
        Masters student
      • Fernando Villalon Letelier
        PhD student

Full University of Melbourne profile