Dr Margaret Littlejohn is a Senior Medical Scientist within the Molecular Research and Development laboratory at the Victorian Infectious Diseases Reference Laboratory (VIDRL). Her current role in the laboratory includes both work on research projects and a diagnostic component. Margaret’s main research focus relates to chronic hepatitis B virus (HBV) infection in Indigenous Australians. Other research interests include HBV viral evolution, antiviral resistance, transmission studies and HIV/HBV co-infection. Margaret’s contribution to the diagnostic work in the laboratory includes development and continuing use of diagnostic tests involved in diagnosis, identification and characterisation of clinically significant mutations of HBV.