Defining the impact of universal iron interventions in young children in rural Bangladesh
Biggs group
Project Leader(s): Professor Beverley-Ann Biggs
Collaborator(s): International Centre for Diarrhoeal Disease Research
In collaboration with Dr Sant-Rayn Pasricha, and colleagues at the International Centre for Diarrhoeal Disease Researh, this NHMRC-funded trial will assess the clinical benefits and harm of iron supplementation in young infants in a rural setting in Bangladesh.
A strategic vision to drive the control of enteric fever through vaccination (STRATAA)
Dunstan group
Project leader(s): Dr Sarah Dunstan
Collaborator(s): International Centre for Diarrhoeal Disease Research, Bangaldesh; University of Oxford, UK; Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi; Oxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal
Funding: Wellcome Trust
Run throughout Malawi, Bangladesh and Nepal, the overall aim of the Strategic Alliance for Typhoid in Africa and Asia (STRATAA) is to provide the science to underpin the implementation of new vaccines for the control of enteric fever, uniquely, in different epidemiological settings in Africa and Asia. This will include (among other things); providing missing data on disease burden, antibiotic resistance and transmission needed to support and implement conjugate vaccines for enteric fever, establishing the host factors that determine susceptibility to enteric fever to inform vaccine implementation strategies, strengthen research capacity in enteric fever endemic regions of the world and provide the data for vaccine implementation advocacy.
Typhoid Vaccine Acceleration Consortium (TyVAC) - host genomics of immunogenicity substudy
Dunstan group
Project leader(s): Dr Sarah Dunstan
Collaborator(s): Oxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal; International Centre for Diarrhoeal Disease Research, Bangaldesh; University of Oxford, UK
TyVAC is assessing the impact of a Vi-Polysaccharide Conjugate Vaccine in preventing typhoid infection among Nepalese and Bangladeshi children. In collaboration with Oxford University Clinical Research Unit Kathmandu, International Centre for Diarrhoeal Disease Research Bangladesh and Oxford University UK, we are investigating the human genomics of vaccine response
Epidemiology of antimicrobial resistance in malaria
Rogerson group
Project leader(s): Professor Stephen Rogerson
Collaborator(s): University of Dhaka