The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Our Work | COVID-19

Vaccines and Antibodies

Receptor Binding Domain vaccine program

Two vaccine candidates have been developed that represent a next generation vaccine for COVID-19, focusing on the tip of the SARS-CoV-2 virus spike protein - the receptor binding domain (RBD) - and blocking virus attachment and infection. The candidates provide two distinct approaches to introduce the virus RBD to our immune system to generate antibodies that neutralise viral infectivity: RBD protein, represents the tip of the spike in an isolated molecular form, and RBD mRNA, represents the virus genetic sequence that codes for the tip of the spike, which will lead to transient production of the RBD protein.

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