The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Our Work | COVID-19

Clinical and Public Health

Australasian COVID-19 Trial (ASCOT)

The Australasian COVID-19 Trial (ASCOT) is a randomised control trial investigating the best treatments for patients hospitalised with COVID-19, with the aim of preventing deterioration to the point of needing a ventilator. ASCOT uses an adaptive platform so that therapeutics can be added or subtracted depending on performance. Currently, there are three major arms to the platform: antiviral, antibody therapy and anticoagulant interventions.

Project lead


  • Royal Brisbane Hospital Foundation
  • Pratt Foundation
  • BHP
  • Minderoo Foundation
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