The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

Our Work | COVID-19

Clinical and Public Health

Current Projects

  • Australasian COVID-19 Trial (ASCOT)

    The Australasian COVID-19 Trial (ASCOT) is a randomised control trial investigating the best treatments for patients hospitalised with COVID-19, with the aim of preventing deterioration to the point of needing a ventilator.

    Find out more › about Australasian COVID-19 Trial (ASCOT)
  • Australian Partnership for Preparedness Research on Infectious Disease Emergencies (APPRISE)

    APPRISE is a Centre for Research Excellence to improve Australia’s response to infectious disease emergencies. We are coordinating a network of medical, scientific, public health, and ethics researchers across Australia towards enhanced responses to COVID-19, including facilitating funding opportunities across the network.  

    APPRISE has supported a number of studies, including the First Few Hundred Studies, which contributes to Australia-wide surveillance studies in an attempt to characterise the spread of COVID-19 by collecting data from households with confirmed cases. 

    Find out more › about Australian Partnership for Preparedness Research on Infectious Disease Emergencies (APPRISE)
  • The Booster Study

    We are seeking volunteers to participate in study looking at whether a booster Moderna vaccine which fights against the original COVID-19 strain as well as Omicron enhances immunity against COVID-19.

    Find out more › about The Booster Study
  • COVID Digital Asset (COVIDDA)

    As the global death toll from COVID-19 rises, so too has the number of Australian healthcare providers seeking mental health support. Researchers from the University of Melbourne’s Integrated Mental Health Research team are working in collaboration with the Royal Melbourne Hospital, Curve Tomorrow and Phoenix Australia to develop the COVID-19 Digital Asset (COVIDDA) application.

    Find out more › about COVID Digital Asset (COVIDDA)
  • Daily resident clinical screening tool for public sector residential aged care facilities

    VICNISS Coordinating Centre developed and implemented a system used by the public sector residential aged care facilities to record both process and outcome monitoring of daily clinical screening of residents and COVID-19 and influenza testing.

    Find out more › about Daily resident clinical screening tool for public sector residential aged care facilities
  • DISCOVER-HCW

    This study will compare healthcare workers with exposure to COVID-19 patients with non-clinical healthcare workers to confirm risk factors for infections, clinical presentations, and the effectiveness of prevention and control interventions at the individual and health facility level.

    Find out more › about DISCOVER-HCW
  • Epidemiological modelling

    Epidemiological models have been critical to informing national and state policy. Our experts are providing epidemiological advice, disease modelling and/or information sharing on key international working groups and national committees.

    Find out more › about Epidemiological modelling
  • Human Infection Challenge Clinical Trial Facility

    The COVID-19 crisis has highlighted the need to rapidly accelerate clinical trials so that vaccines and treatments can be developed more quickly to prepare for and respond to future pandemics. The Human Infection Challenge (HIC) Clinical Trial Facility will establish and operate a 15-bed facility located at the Royal Melbourne Hospital that will be an extension of the Doherty Institute

    Find out more › about Human Infection Challenge Clinical Trial Facility
  • The Optimise Study

    The Optimise Study is a highly innovative joint study between the Doherty Institute and the Burnet Institute that will provide the Victorian and Federal Governments with timely and high-quality data to assist in making informed, precise and impactful policy during the COVID-19 response. 

    Find out more › about The Optimise Study
  • The Sentinel Travellers and Research Preparedness Platform for Emerging Infectious Disease (SETREP-ID)

    SETREP-ID is a clinical research platform that has been activated within hospitals across Victoria to collect key biological samples from patients with COVID-19 to understand virus shedding and the immune system response.  

    Find out more › about The Sentinel Travellers and Research Preparedness Platform for Emerging Infectious Disease (SETREP-ID)
  • Transmission dynamics, surface decontamination and disinfection

    Transmission dynamics is important for understanding how COVID-19 spreads through populations and environments. There is limited knowledge of how long and under what conditions the virus is able to survive on surfaces, both wet and dry, cold and hot. 

    Find out more › about Transmission dynamics, surface decontamination and disinfection
  • Victorian COVID-19 Vaccinees Collection

    The Victorian COVID-19 Vaccinees Collection (VC²) is a biospecimen collection – or biobank – of samples from people vaccinated against COVID-19 in Victoria.

    Find out more › about Victorian COVID-19 Vaccinees Collection
  • Aerosol transmission and mitigation strategies in clinical settings

    This project looks at aerosol transmission and mitigation strategies in a clinical setting.

    Find out more › about Aerosol transmission and mitigation strategies in clinical settings
  • COVID-AIMS

    This is a longitudinal study collecting blood samples from COVID-19 patients to understand immune responses, household transmission and psycho-social impacts from public health interventions.

    Find out more › about COVID-AIMS
  • Experiences of Australian aged care workers in relation to Infection Prevention and Control (IPC) measures during COVID-19 pandemic

    In order to protect residents, staff, and the wider community, it is critical to evaluate and understand the adequacy and challenges of IPC measures in aged care outbreaks. This research project will use qualitative methodology to capture and illuminate the experiences of aged care workers using IPC measures.

    Find out more › about Experiences of Australian aged care workers in relation to Infection Prevention and Control (IPC) measures during COVID-19 pandemic