Current Projects
-
Evaluating direct and indirect effects of SARS-CoV-2 on multiple organ systems using stem cell-derived human tissues
This multi-agency study unites the expertise of world leaders in their field to use human-derived stem cells to better understand the effects of SARS-CoV-2 on a wide variety of different organ systems in the body.
Find out more › about Evaluating direct and indirect effects of SARS-CoV-2 on multiple organ systems using stem cell-derived human tissues -
Preparing animal models
Once potential vaccines and therapeutic candidates have been identified, they must be tested in animals to predict the response in humans and determine overall efficacy. This will occur in partnership with Parkville Precinct collaborators and AgriBio.
Find out more › about Preparing animal models -
Testing SARS-CoV-2 vaccine and therapeutics using human respiratory epithelium and organoid models
There is pressing urgency to develop vaccines and therapies to treat patients with COVID-19. This project will enable the production and utilisation of tissue-restricted stem-cell derived organoids to further our understanding of SARS-CoV-2 and the biological basis for infection.
Find out more › about Testing SARS-CoV-2 vaccine and therapeutics using human respiratory epithelium and organoid models -
Isolating and understanding fitness of various SARS-CoV-2 variants of concern.
This project will focus on isolating and understanding fitness of various SARS-CoV-2 variants of concern.
Find out more › about Isolating and understanding fitness of various SARS-CoV-2 variants of concern. -
Using CRISPR-Cas13 as an antiviral for SARS-CoV-2
This discovery builds on research which started at Peter Mac in 2019 – when Dr Mohamed Fareh and Professor Joe Trapani showed a CRISPR gene editing tool could be used to eliminate abnormal RNAs that drive children’s cancers.
Find out more › about Using CRISPR-Cas13 as an antiviral for SARS-CoV-2