The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

  • Research Groups
    • VICNISS

      The VICNISS Coordinating Centre provides a state-wide, standardised surveillance service for healthcare associated infections (HAIs) and related events. The goal of VICNISS is to monitor and reduce the incidence of HAIs, providing support for health services in Victoria. VICNISS aims to support Victorian health services to carry out international best practice surveillance and analysis, and to lead interventions for quality improvement to improve the health of all Victorians.

      VICNISS provides a source of high quality data for regular performance monitoring, and for a valuable resource for the research community. Over the time of VICNISS surveillance, infection rates in key areas of focus have fallen markedly, reducing the significant financial and personal cost of these infections on both individual patients and the health system.

      VICNISS collaborates with the National Centre for Antimicrobial Stewardship (NCAS), with a major involvement in aged care NAPS (ac-NAPS). VICNISS is also engaged by DHHS Residential Aged Care Services to carry out monitoring of infection control indicators in Victoria’s public residential aged care services, including participation in ac-NAPS.


    Current Projects

    • Infections and events monitored by the coordinating centre include:

      - Line-associated bloodstream infections in intensive care units (adult, paediatric and neonatal)

      - Line associated bloodstream infections outside of intensive care units

      - Ventilator-associated events in intensive care units

      - Surgical site infections

      - Staphylococcus aureus bloodstream infections in patients admitted to hospital

      - Clostridium difficile infections

      - Haemodialysis related infectious events

      - Methicillin-resistant S.aureus infections and vancomycin-resistant enterococcal infections

      - Carbapenamase-resistant enterobacteriaceae (in collaboration with DHHS)

      - Occupational exposures of healthcare workers to blood and body fluids

      - Healthcare worker seasonal influenza vaccination

      - Surgical antibiotic prophylaxis compliance

      - Peripheral venous catheter use

    • Community Staphylococcus aureus infections

      Hospitals in Victoria submit data on all hospitalised S.aureus bloodstream infections, including those considered to be “community acquired”. Rates of infection have undergone a considerable increase in recent years, and VICNISS is currently investigating in conjunction with colleagues in Western Australia observing a similar increase. We are also consulting with MDU on this project, and may undertake collaborative work to investigate possible causes of this increase.

    • Surgical antibiotic prophylaxis

      Having access to a very large database of compliance and outcome data allows us to investigate many aspects of surgical prophylaxis. We are comparing the effectiveness of different antibiotic regimens for various surgical procedures.

      VICNISS is investigating the differences in infection outcome when intra-operative re-dosing was and was not recorded as being performed for lengthy surgical procedures.

    • Infections and antimicrobial use in residential aged care

      Using data collated in pilot programs in Victoria preceding ac-NAPS, and data from the ac-NAPS surveys, VICNISS and NCAS have published a series of articles focussing on the prevalence of infections and antimicrobial usage in residential aged care homes.

    • Trends in infection rates in Victoria

      The VICNISS team regularly publish analyses of infection rates, pathogens and related indicators in Victoria to examine trends.


    Lab Team

    VICNISS