The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

HIV | Current projects

Interested in HIV cure research? (Vitamin D study)

About the research study

In patients with HIV on antiretroviral therapy (ART), HIV hides in immune cells called CD4+ T cells which is why ART is not curative. HIV hides most efficiently in the gut because of local inflammation that impairs the immune response. Vitamin D reduces inflammation in the gut and may increase the ability of the immune system to recognise and eliminate infected cells. In this study participants will receive either high dose vitamin D or an inactive pill for 6 months and will have blood tests 3 monthly for 9 months. They will remain on your HIV treatment throughout.

This study is now closed to recruitment.

Approved by Melbourne Health 2016.362 (multisite HREC/16/MH/385) for study entitled “Effect of high dose vitamin D supplementation on HIV latency: A pilot randomised controlled trial (VIVA trial)”

Principal investigator