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Publications

Browse publications attributed to Doherty Institute researchers

Overview

Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Dr Annabell Bachem (24)

CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses.

2025 · journal-article
Whereas CD4+ T cells conventionally mediate antitumor immunity by providing help to CD8+ T cells, recent clinical studies have implied…

Functional flexibility and plasticity in immune control of systemic Salmonella infection.

2025 · journal-article
Immunity to systemic Salmonella infection depends on multiple effector mechanisms. Lymphocyte-derived interferon gamma (IFN-γ) enhances cell-intrinsic bactericidal capabilities to antagonize…

CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.

2025 · journal-article
Antiviral CD8+ T cell immunity depends on the integration of various contextual cues, but how antigen-presenting cells (APCs) consolidate these…

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.

2025 · journal-article
Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necroptosis, and apoptosis during…

Effective Priming of Herpes Simplex Virus-Specific CD8 + T Cells In Vivo Does Not Require Infected Dendritic Cells

2025 · journal-article
ABSTRACT Resolution of virus infections depends on the priming of virus-specific CD8 + T cells by dendritic cells (DC). While…

High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.

2024 · journal-article
Respiratory infections cause significant morbidity and mortality, yet it is unclear why some individuals succumb to severe disease. In patients…

GPR41 and GPR43 regulate CD8<sup>+</sup> T cell priming during herpes simplex virus type 1 infection.

2024 · journal-article
Naïve CD8+ T cells need to undergo a complex and coordinated differentiation program to gain the capacity to control virus…

Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches.

2022 · journal-article
Reinvigoration of exhausted CD8+ T (Tex) cells by checkpoint immunotherapy depends on the activation of precursors of exhausted T (Tpex)…

TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs.

2021 · journal-article
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections…

Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.

2021 · journal-article
Tissue-resident memory T cells (TRM cells) are key elements of tissue immunity. Here, we investigated the role of the regulator…

Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response.

2020 · journal-article
Mitochondrial OXPHOS generates most of the energy required for cellular function. OXPHOS biogenesis requires the coordinated expression of the nuclear…
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