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Browse publications attributed to Doherty Institute researchers

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Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Dr Maria Daglas (21)

Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injury

2025 · journal-article
AbstractRepetitive mild traumatic brain injury (r-mTBI) has increasingly become recognised as a risk factor for the development of neurodegenerative diseases,…

The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.

2025 · journal-article
The neurovascular unit provides a dynamic interface between the circulation and central nervous system. Disruption of neurovascular integrity occurs in…

Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes.

2025 · journal-article
BackgroundLysophosphatidic acid (LPA) is a bioactive phospholipid with a potentially causative role in neurotrauma. Blocking LPA signaling with the LPA-directed…

Evaluation of gait impairment in mice subjected to craniotomy and traumatic brain injury.

2025 · journal-article
Traumatic brain injury (TBI) represents a significant global health burden and causes long-lasting neuromotor deficits, particularly in individuals who sustain…

Altered amyloid precursor protein, tau-regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1 month following repetitive mild traumatic brain injury.

2025 · journal-article
Repetitive mild traumatic brain injury, commonly experienced following sports injuries, results in various secondary injury processes and is increasingly recognised…

Traumatic brain injury opens blood-brain barrier to stealth liposomes via an enhanced permeability and retention (EPR)-like effect.

2025 · journal-article
The opening of the tight junctions in the blood-brain barrier (BBB) following traumatic brain injury (TBI) is hypothesized to be…

Valproic acid selectively increases vascular endothelial tissue-type plasminogen activator production and reduces thrombus formation in the mouse.

2025 · journal-article
Essentials Stimulating endogenous fibrinolysis could be a novel antithrombotic strategy. The effect of valproic acid on endothelial tissue plasminogen activator…

The Involvement of Iron in Traumatic Brain Injury and Neurodegenerative Disease

2025 · journal-article

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

2025 · journal-article
Abstract Tranexamic acid (TXA) is an antifibrinolytic agent that blocks plasmin formation. Because plasmin is known to promote inflammatory and…

Zinc and traumatic brain injury

2023 · book-chapter

Deferiprone attenuates neuropathology and improves outcome following traumatic brain injury

2023 · journal-article
Background and PurposeTraumatic brain injury (TBI) remains a leading cause of mortality and morbidity in young adults. The role of…

Characterization of the spatial distribution of metals and profile of metalloprotein complexes in a mouse model of repetitive mild traumatic brain injury

2022 · journal-article
AbstractMetal dyshomeostasis is a well-established consequence of neurodegenerative diseases and traumatic brain injury. While the significance of metals continues to…

Tau Pathology, Metal Dyshomeostasis and Repetitive Mild Traumatic Brain Injury: An Unexplored Link Paving the Way for Neurodegeneration.

2022 · journal-article
Repetitive mild traumatic brain injury (r-mTBI), commonly experienced by athletes and military personnel, causes changes in multiple intracellular pathways, one…

The adaptive immune system in traumatic brain injury: A focus on T and B lymphocytes

2022 · book-chapter

Sex‐dependent effects of tranexamic acid on blood‐brain barrier permeability and the immune response following traumatic brain injury in mice

2020 · journal-article

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

2019 · journal-article

Tranexamic Acid Influences the Immune Response, but not Bacterial Clearance in a Model of Post-Traumatic Brain Injury Pneumonia

2019 · journal-article

Activated CD8 T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

2019 · journal-article
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