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Publications

Browse publications attributed to Doherty Institute researchers

Overview

Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Professor Bill Heath (398)

Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression.

2025 · journal-article
Blood-borne pathogens can cause systemic inflammatory response syndrome (SIRS) followed by protracted, potentially lethal immunosuppression. The mechanisms responsible for impaired…

mRNA vaccine against malaria tailored for liver-resident memory T cells.

2025 · journal-article
Malaria is caused by Plasmodium species transmitted by Anopheles mosquitoes. Following a mosquito bite, Plasmodium sporozoites migrate from skin to…

Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis.

2025 · journal-article
Plasmodium replicates within the liver prior to reaching the bloodstream and infecting red blood cells. Because clinical manifestations of malaria…

Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes.

2025 · journal-article
Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the key events controlling TRM cell development is the…

Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity.

2025 · journal-article
Tissue-resident memory T (TRM) cells are non-recirculating cells that exist throughout the body. Although TRM cells in various organs rely…

Plasmodium berghei Hsp90 contains a natural immunogenic I-Ab-restricted antigen common to rodent and human Plasmodium species.

2025 · journal-article
Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by the study of responses…

Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells.

2024 · journal-article
Background & aimsLiver diseases resulting from chronic HBV infection are a significant cause of morbidity and mortality. Vaccines that elicit…

Complexing CpG adjuvants with cationic liposomes enhances vaccine-induced formation of liver TRM cells.

2023 · journal-article
Tissue resident memory T cells (TRM cells) can provide effective tissue surveillance and can respond rapidly to infection. Vaccination strategies…

Marginal zone B cells acquire dendritic cell functions by trogocytosis.

2022 · journal-article
Marginal zone (MZ) B cells produce broad-spectrum antibodies that protect against infection early in life. In some instances, antibody production…

Differential location of NKT and MAIT cells within lymphoid tissue.

2022 · journal-article
Natural Killer T (NKT) cells and Mucosal-Associated Invariant T (MAIT) cells are innate-like T cells that express semi-invariant αβ T…

6″-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria.

2022 · journal-article
Self-adjuvanting vaccines consisting of peptide epitopes conjugated to immune adjuvants are a powerful way of generating antigen-specific immune responses. We…

Using Full-Spectrum Flow Cytometry to Phenotype Memory T and NKT Cell Subsets with Optimized Tissue-Specific Preparation Protocols.

2022 · journal-article
Full-spectrum flow cytometry is now routinely used in many laboratories internationally, and the demand for this technology is rapidly increasing.…
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