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Publications

Browse publications attributed to Doherty Institute researchers

Overview

Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Professor Elizabeth Vincan (68)

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy.

2025 · book-chapter
The Wnt pathway is at the heart of organoid technology, which is set to revolutionize the cancer field. We can…

Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth

2025 · journal-article
ZRANB1 (human Trabid) missense mutations have been identified in children diagnosed with a range of congenital disorders including reduced brain…

Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery.

2025 · journal-article
The introduction of directly acting antiviral agents (DAAs) has produced significant improvements in the ability to cure chronic hepatitis C…

Organoids Are Us

2025 · journal-article

HBV-related hepatocarcinogenesis: the role of signalling pathways and innovative ex vivo research models.

2025 · journal-article
BACKGROUND:Hepatitis B virus (HBV) is the leading cause of liver cancer, but the mechanisms by which HBV causes liver cancer…

Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models

2025 · journal-article
AbstractA major unmet clinical need is a therapeutic capable of removing hepatitis B virus (HBV) genome from the liver of…

Uncovering strain- and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using 10X single-cell sequencing

2023 · preprint
SummaryAssessing the impact of SARS-CoV-2 variants on the host is crucial with continuous emergence of new variants. We employed single-cell…

Assessment of hepatitis B virus infection and interhost cellular responses using intrahepatic cholangiocyte organoids

2023 · journal-article
AbstractThe intrahepatic cholangiocyte organoids (ICOs) model was evaluated for host differences in hepatitis B virus (HBV) infection, cellular responses, antiviral…
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