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Browse publications attributed to Doherty Institute researchers

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Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Dr Thomas Rasmussen (83)

Factors influencing virologic control during analytical treatment interruptions in HIV cure trials – a pooled analysis of individual level data

2025 · journal-article
Background. Achieving antiretroviral therapy (ART)-free virologic control remains a central goal in human immunodeficiency virus (HIV) cure research. To identify…

Protocol for measuring killing capacity and intracellular cytokine production of human HIV antigen-specific CD8 T cells using flow cytometry

2025 · journal-article
Here, we present a protocol to evaluate the killing capacity and functional profile of human HIV-specific CD8 T cells. We…

Kick and kill for HIV latency.

2025 · journal-article

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls.

2025 · journal-article
BackgroundA research priority in finding a cure for HIV is to establish methods to accurately locate and quantify where and…

Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency.

2025 · journal-article
BackgroundOne strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy…

Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound

2025 · journal-article
OBJECTIVE: This study aimed to identify candidate host epigenetic biomarkers predicting latency reversal agents (LRA) efficacy and HIV-1 rebound kinetics…

Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency

2025 · journal-article
Programmed cell death 1 (PD1) and cytotoxic T lymphocyte-associated protein 4 (CTLA4) suppress CD4+ T cell activation and may promote latent…

Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4

2025 · journal-article
INTRODUCTION: HIV-1 persists in resting CD4+ T-cells despite antiretroviral therapy (ART). Determining the cell surface markers that enrich for genetically-intact…

Meeting Summary for Keystone Symposia on HIV Cure

2025 · journal-article
Antiretroviral therapy (ART) can effectively control human immunodeficiency virus (HIV) replication; however, lifelong treatment is required due to viral reservoirs,…

Pomalidomide enhances CD8+ T and NK cell mediated killing of HIV-infected cells

2025 · journal-article
Background: Overcoming persisting immune dysfunction in people living with HIV (PLHIV) on suppressive antiretroviral therapy (ART) is a key challenge…

Targeting Ikaros and Aiolos with pomalidomide fails to reactivate or induce apoptosis of the latent HIV reservoir

2025 · journal-article
HIV persists in people living with HIV (PLHIV) on antiretroviral therapy (ART) in long-lived and proliferating latently infected CD4+ T…

Cutaneous leishmaniasis in a patient with psoriatic arthritis treated with tumour necrosis factor-α inhibitor

2024 · journal-article

Clinical trials aimed at HIV cure or remission

2023 · journal-article
INTRODUCTION: The main barrier to finding a cure against HIV is the latent HIV reservoir, which persists in people living…

GITR activation exvivo impairs CD8 T cell function in people with HIV on antiretroviral therapy

2023 · journal-article
Glucocorticoid-induced tumor necrosis factor related protein (GITR) is a co-stimulatory immune checkpoint molecule constitutively expressed on regulatory T cells (Tregs)…

Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence

2023 · journal-article
Inducing antiretroviral therapy (ART)-free virological control is a critical step toward a human immunodeficiency virus type 1 (HIV-1) cure. In…

Effect of high dose vitamin D3 on the HIV-1 reservoir

2023 · journal-article
INTRODUCTION: Antiretroviral therapy for people living with HIV-1 must be taken lifelong due to the persistence of latent virus in…

Immunomodulation with IL-7 and IL-15 in HIV-1 infection

2023 · journal-article
Immunomodulating agents are substances that modify the host immune responses in diseases such as infections, autoimmune conditions and cancers. Immunomodulators…

Experience with Sotrovimab treatment of SARS-CoV-2 infected patients in Denmark

2023 · journal-article
OBJECTIVE: To evaluate the experience with use of Sotrovimab following Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) infection in high-risk…
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