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Browse publications attributed to Doherty Institute researchers

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Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Professor Andrew Brooks (194)

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.

2025 · journal-article
Indigenous people worldwide are at high risk of developing severe influenza disease. HLA-A*24:02 allele, highly prevalent in Indigenous populations, is associated…

The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.

2025 · journal-article
HLA class I molecules that represent ligands for the inhibitory killer cell Ig-like receptor (KIR) 3DL1 found on NK cells…

Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

2025 · journal-article
BackgroundAnti-viral treatments to control cytomegalovirus (CMV) after lung transplantation (LTx) are associated with toxicity and anti-viral resistance. Cellular immunotherapy with…

Harnessing HLA-E-restricted CD8 T lymphocytes for adoptive cell therapy of patients with severe COVID-19.

2025 · journal-article

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.

2025 · journal-article
Micropolymorphisms within human leukocyte antigen (HLA) class I molecules can change the architecture of the peptide-binding cleft, leading to differences…

The complex existence of γδ T cells following transplantation: the good, the bad and the simply confusing.

2025 · journal-article
Gamma delta (γδ) T cells are a highly heterogeneous population of lymphocytes that exhibit innate and adaptive immune properties. Despite…

Downregulation of MHC Class I Expression by Influenza A and B Viruses.

2025 · journal-article
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface expression, is used by many viruses to evade…

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection.

2025 · journal-article
CD4+ T cell responses are crucial for the control of many intracellular pathogens, yet the requirements for their induction are…

Activating KIR Haplotype Influences Clinical Outcome Following HLA-Matched Sibling Hematopoietic Stem Cell Transplantation.

2025 · journal-article
Natural killer cells are thought to influence the outcome of hematopoietic stem cell transplant (HSCT), impacting on relapse, overall survival,…

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.

2025 · journal-article
αβ T cell receptors (TCRs) interact with peptides bound to the polymorphic major histocompatibility complex class Ia (MHC-Ia) and class…

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.

2025 · journal-article
Human leukocyte antigen (HLA)-C*06:02 is identified as the allele associated with the highest risk for the development of the autoimmune…

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells

2025 · journal-article
The lymphoid tissue that drains the upper respiratory tract represents an important induction site for cytotoxic T lymphocyte (CTL) immunity…

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

2025 · journal-article
Major histocompatibility complex class I (MHC-I) molecules play a crucial role in immunity by capturing peptides for presentation to T…

Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses.

2025 · journal-article
Many insights regarding the pathogenesis of human influenza A virus (IAV) infections have come from studies in mice and ferrets.…

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus.

2025 · journal-article
It is well established that influenza A virus (IAV) attachment to and infection of epithelial cells is dependent on sialic…

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle.

2025 · journal-article
Airway epithelial cells are susceptible to infection with seasonal influenza A viruses (IAV), resulting in productive virus replication and release.…

The Presence of HLA-E-Restricted, CMV-Specific CD8+ T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

2025 · journal-article

Specific Sites of N-Linked Glycosylation on the Hemagglutinin of H1N1 Subtype Influenza A Virus Determine Sensitivity to Inhibitors of the Innate Immune System and Virulence in Mice

2025 · journal-article
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