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Publications

Browse publications attributed to Doherty Institute researchers

Overview

Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Professor Jason Mackenzie (96)

TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation.

2025 · journal-article
Norovirus infections are a significant health and economic burden globally, accounting for hundreds of millions of cases of acute gastroenteritis…

Downregulation of MHC Class I Expression by Influenza A and B Viruses.

2025 · journal-article
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface expression, is used by many viruses to evade…

Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection.

2025 · journal-article
Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine…

Determinants of Zika virus host tropism uncovered by deep mutational scanning.

2025 · journal-article
Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and…

Modulation of acyl-carnitines, the broad mechanism behind Wolbachia -mediated inhibition of medically important flaviviruses in Aedes aegypti

2025 · journal-article
Significance Wolbachia ( w Mel strain)-infected Aedes aegypti mosquitoes are refractory to disseminated arboviral infections. Yet previous studies into the…

Lipid droplets and lipid mediators in viral infection and immunity

2025 · journal-article
Abstract Lipid droplets (LDs) contribute to key pathways important for the physiology and pathophysiology of cells. In a homeostatic view,…

SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon

2025 · journal-article
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral infection. Resultantly, many…

Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus.

2025 · journal-article
Positive-sense RNA virus intracellular replication is intimately associated with membrane platforms that are derived from host organelles and comprised of…

Broad-spectrum non-nucleoside inhibitors for caliciviruses.

2025 · journal-article
Viruses of the Caliciviridae cause significant and sometimes lethal diseases, however despite substantial research efforts, specific antivirals are lacking. Broad-spectrum…
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