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Browse publications attributed to Doherty Institute researchers

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Research publications at the Doherty Institute

Our commitment to advancing knowledge in infectious diseases and immunology is reflected in a growing body of peer-reviewed research. This page provides access to published studies from our world-class scientists and collaborators, showcasing breakthroughs that inform policy, improve clinical practice, and drive innovation to improve health outcomes. Browse our collection to stay informed on the latest scientific insights shaping the future.

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Showing publications from Dr Michael Roche (70)

CRISPR/Cas9 for achieving postintervention HIV control.

2025 · journal-article
Purpose of reviewRecent advances in gene therapy have led to the first clinically approved CRISPR/Cas9 therapy for β-thalassaemia and sickle…

Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains.

2025 · journal-article
Seasonal human coronaviruses (sHCoVs) cause 15%-30% of common colds. The reference strains used for research were isolated decades ago and…

Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains.

2025 · journal-article
Seasonal human coronaviruses (sHCoVs) cause 15%-30% of common colds. The reference strains used for research were isolated decades ago and…

Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains.

2025 · journal-article
Seasonal human coronaviruses (sHCoVs) cause 15%-30% of common colds. The reference strains used for research were isolated decades ago and…

Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.

2025 · journal-article
People with human immunodeficiency virus-hepatitis B virus (HIV-HBV) co-infection have faster rates of liver disease progression and an increase in…

Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.

2025 · journal-article
People with human immunodeficiency virus-hepatitis B virus (HIV-HBV) co-infection have faster rates of liver disease progression and an increase in…

Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.

2025 · journal-article
People with human immunodeficiency virus-hepatitis B virus (HIV-HBV) co-infection have faster rates of liver disease progression and an increase in…

CRISPR/Cas9 for achieving postintervention HIV control.

2025 · journal-article
Purpose of reviewRecent advances in gene therapy have led to the first clinically approved CRISPR/Cas9 therapy for β-thalassaemia and sickle…

CRISPR/Cas9 for achieving postintervention HIV control.

2025 · journal-article
Purpose of reviewRecent advances in gene therapy have led to the first clinically approved CRISPR/Cas9 therapy for β-thalassaemia and sickle…

Efficient mRNA delivery to resting T cells to reverse HIV latency.

2025 · journal-article
A major hurdle to curing HIV is the persistence of integrated proviruses in resting CD4+ T cells that remain in…

Understanding the mechanisms driving the spread of subtype C HIV-1.

2025 · journal-article
Human immunodeficiency virus type 1 (HIV-1) subtype C (C-HIV) is the most prevalent form of HIV-1 globally, accounting for approximately…

CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4+ T Cells in People Living with HIV on Antiretroviral Therapy: Implications for How Latency Is Established and Maintained.

2025 · journal-article
HIV can persist in people living with HIV (PLWH) on antiretroviral therapy (ART) in multiple CD4+ T cell subsets, including…

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls.

2025 · journal-article
BackgroundA research priority in finding a cure for HIV is to establish methods to accurately locate and quantify where and…

Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency.

2025 · journal-article
BackgroundOne strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy…

The role of oxidative stress in HIV-associated neurocognitive disorders.

2025 · journal-article
HIV-associated neurocognitive disorders (HAND) are a leading cause of morbidity in up to 50% of individuals living with HIV, despite…

Modular Lentiviral Vectors for Highly Efficient Transgene Expression in Resting Immune Cells.

2025 · journal-article
Gene/cell therapies are promising strategies for the many presently incurable diseases. A key step in this process is the efficient…

Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy

2025 · journal-article

Factors associated with weak positive SARS-CoV-2 diagnosis by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR).

2025 · journal-article
During the COVID-19 pandemic, the reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) assay has been the primary method of diagnosis of…
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