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A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial


I. Russel Lee, Steven Y.C. Tong, Joshua S. Davis, David L. Paterson, Sharifah F. Syed-Omar, Kwong Ran Peck, Doo Ryeon Chung, Graham S. Cooke, Eshele Anak Libau, Siti Nabilah B.A. Rahman, Mihir P. Gandhi, Luming Shi, Shuwei Zheng, Jenna Chaung, Seow Yen Tan, Shirin Kalimuddin, Sophia Archuleta, David C. Lye


Trials, Volume 23, Issue 1, 2022-12-01, Article number 572

Article Link: Click here


  • National Centre for Infectious Diseases
  • School of Medicine and Public Health
  • UQ Centre for Clinical Research
  • Duke-NUS Medical School
  • National University Hospital
  • NUS Yong Loo Lin School of Medicine
  • University of Melbourne
  • Samsung Medical Center, Sungkyunkwan University
  • Singapore General Hospital
  • Imperial College London
  • University of Malaya Medical Centre
  • Changi General Hospital
  • Nanyang Technological University
  • Tan Tock Seng Hospital
  • Sengkang General Hospital
  • Consortium for Clinical Research and Innovation
  • Ng Teng Fong General Hospital