The Batman and Robin of liver-stage immunity to malaria
Authors:
- Heath, William R.
- Holz, Lauren E.
- Fernandez-Ruiz, Daniel
Details:
Trends in Parasitology, Volume 38, Issue 1, 2022-01-31
Article Link: Click here
Malaria parasites replicate within the liver shortly after infection. This stage can be controlled by CD8 T cells, but which subsets undertake this function is unclear. Lefebvre et al. now elegantly show that effector memory T (TEM) cells are avid participants, working as a dynamic duo with liver tissue-resident memory T (TRM) cells to combat infection.