Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance

Author(s):

Mohamed Fareh, Wei Zhao, Wenxin Hu, Joshua M.L. Casan, Amit Kumar, Jori Symons, Jennifer M. Zerbato, Danielle Fong, Ilia Voskoboinik, Paul G. Ekert, Rajeev Rudraraju, Damian F.J. Purcell, Sharon R. Lewin, Joseph A. Trapani

Details:

Nature Communications, Volume 12, Issue 1, 2021-12-01, Article number 4270

Article Link: Click here

Affiliations:

• The Peter Doherty Institute for Infection and Immunity
• Cancer Institute NSW
• Peter Maccallum Cancer Centre
• University of Melbourne
• Murdoch Children's Research Institute
• The Alfred