The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

13 Feb 2020

Uncovering resident macrophages of the mammary gland by 3D and intravital imaging

Add to my calendar 13/02/2020 11:57 am Australia/Melbourne Uncovering resident macrophages of the mammary gland by 3D and intravital imaging Auditorium DD/MM/YYYY

WHEN
13 Feb 2020
12.00pm

WHERE
Auditorium

At this special seminar Dr Caleb Dawson, Postdoctoral Researcher, Walter and Eliza Hall Institute of Medical Research, will present his work on Uncovering resident macrophages of the mammary gland by 3D and intravital imaging.

Caleb Dawson will talk about a novel population of resident ‘ductal macrophages’ that are intimately associated with the mammary epithelium. He will describe their behaviour, origin, function and dynamics throughout mammary gland remodellingusing 3D and intravital imaging, fate mapping and in vivo depletion models. Ductal macrophages play a key role during gland involution post-lactation and have a striking relationship with breast tumour-associated macrophages. The mammary gland remodels dramatically throughout adult life and is highly susceptible to cancer, making it a unique model for studying immune regulation of development and remodellingand how this influences tumorigenesis.