28 Feb 2020
The Pathogenesis of Cerebral Malaria – more pieces of the puzzle
28 Feb 2020
12.00 - 1.00pm
At this special seminar, Professor Terrie Taylor University Distinguished Professor and MSU Foundation Professor, College of Osteopathic Medicine, University of Michigan and Scientific Director, Blantyre Malaria Project, College of Medicine, University of Malawi, will speak on The Pathogenesis of Cerebral Malaria – more pieces of the puzzle.
Professor Taylor has been living and working in Malawi for six straight months each year (January – June, the “malaria season”) since 1986. Her focus has been on the pathogenesis of cerebral malaria. Her team provides clinical care for children with cerebral malaria and, in that context, study the disease. This has included conducting four interventional clinical trials, recognizing malarial retinopathy and establishing its importance, orchestrating the largest single autopsy study of fatal cerebral malaria, and coordinating the introduction of magnetic resonance imaging in Malawi.
The children hospitalised on the Paediatric Research Ward in Blantyre are the most exhaustively characterised cerebral malaria patients in the world. In early 2018, they started an interventional clinical trial comparing immediate hyperventilation or hypertonic saline to usual care in Malawian children with CM and increased brain volume. They hope that this study will support other investigations into the etiology of increased brain volume in this patient population.