One Health
Genomic Characterisation of E. coli from persistent or recurrent canine urinary tract infections
Project Summary
Escherichia coli is an important cause of urinary tract infections in dogs. While some dogs will present with clinical symptoms others will be asymptomatic. Little is known about the factors that might be responsible for these different disease outcomes.
A number of E. coli isolates have been collected from dogs with clinical and asymptomatic urinary tract infections.
The aims of this project are to 1) determine which strain types are associated with canine UTI, 2) determine whether particular strain types are associated with clinical vs asymptomatic disease, and 3) investigate whether the presence of certain virulence factors and antibiotic resistance genes are associated with particular disease outcomes.
Project Partners
Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Australia