One Health (Past Projects)
Cefotaxime Resistant Salmonella enteritidis Serovar
Salmonellosis is an important cause of bacterial gastroenteritis in Australia. Reported rates of antimicrobial resistance in locally-acquired strains of Salmonella enterica serovar Typhimurium are low compared with other countries, with no third-generation cephalosporin resistance reported. Since 2012, resistance to cefotaxime has been noted in multi-drug resistant (MDR) isolates of S. enterica serovar Typhimurium phage-type 44 (STm44) obtained from humans and food animals in Victoria.
This study aims to characterise the resistance mechanism and investigate the emergence of this non-susceptible strain, using a combination of phenotypic methods and whole-genome sequencing (WGS).
OzFoodNet, ACT, Australia
Department of Health and Human Services, Victoria, Australia
Sparham SJ, Kwong JC, Valcanis M, Easton M, Trott DJ, Seemann T, Stinear TP, Howden BP. International Journal of Antimicrobial Agents. 2017;50(1):101-5. doi: 10.1016/j.ijantimicag.2017.02.014