The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Understanding immunodominance hierarchies of CD4 T follicular helper cells

Juno Group

CD4+ T follicular helper (Tfh) cells in lymph nodes are critical to the generation of effective neutralising antibody responses to infection and vaccination. Using our well developmed mouse models of prototype vaccines against influenza and SARS-CoV-2, this project will seek to underestand how prominent or subdominant CD4 T cell responses contribute to germinal centre development and elicitation of high quality antibody responses. 

Contact project supervisor for further
information and application enquiries

Project Supervisor

Dr Jennifer Juno

Project Co-supervisor

Dr Adam Wheatley

Project availability

Juno Group

0 vacancies

Viral Infectious Diseases
Cross Cutting Disciplines
Discovery Research

The Juno group is interested in the biogenesis of CD4 T follicular helper cells and their capacity to promote high quality antibody responses following infection or vaccination. Our major focus is immunity to viral infections such as influenza, SARS-CoV-2 and HIV. The lab uses a combination of human clinical samples and pre-clinical animal models to understand the phenotypic and functional characteristics of diverse CD4 T cell populations.