The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Precision genomics for antimicrobial-resistant bacterial pathogens

Howden Group

Antimicrobial-resistant bacterial pathogens are one of the foremost threats to global public health today. Whole genome sequencing holds great potential for monitoring, and therefore limiting, continued transmission of these difficult-to-treat pathogens. The project will investigate the genomics of antimicrobial-resistant bacterial pathogens typically found causing invasive disease in hospital- and healthcare-associated environments. It will involve the application of bioinformatic approaches to combined epidemiological and genomic data associated, in order to better understand the evolution and spread of these pathogens.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Dr Claire Gorrie

Project Co-supervisor

Professor Benjamin Howden

Project availability
Master of Biomedical Science

Howden Group

3 vacancies

Antimicrobial Resistance and Healthcare Associated Infections
Host Pathogens Interactions
Cross Cutting Disciplines
Global Health
Indigenous Health

Research Projects 2019 | 19 The Howden group is embedded in the state public health laboratory - the Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL) - with expertise in pathogen genomics and antimicrobial resistance, including functional genomics technologies and models of disease. We complement these molecular biology studies with epidemiological and clinical studies to address a broad range of issues related to invasive bacterial diseases in humans, especially those caused by staphylococci, enterococci and other antimicrobial-resistant species (CPE). Working closely with scientists in the MDU PHL, we investigate the epidemiology, evolution and spread of bacterial pathogens of public health significance such as Neisseria gonorrhoea, Listeria monocytogenes, Legionella spp. and Salmonella spp.