Project: Neural regulation of anti-cancer immunity
Mueller Group
Cancer is a highly stressful experience and this stress may impair immune responses that could fight disease. How stress responses by the sympathetic nervous system can alter immunity to tumours is not known. This project will investigate how neural signals impact immune responses in the tumour microenvironment, in order to design new therapies to treat cancer. Techniques used in this work include advanced spectral microscopy and in vivo 3-photon imaging, spectral flow cytometry and single cell RNA sequencing, custom imagage analysis tools.
Contact project supervisor for further
information and application enquiries
Mueller Group
5 vacancies
Research in the Mueller group is focused on examining immune responses and nervous system interactions during acute and chronic viral infections and in cancer. We are seeking a fundamental understanding of biology and new treatments for disease. We are using state-of-the-art methods, including advanced microscopy, spectral flow cytometry, single cell sequencing and bioinformatics.
Mueller Group Current Projects
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Neural regulation of anti-cancer immunity
PhD/MPhil, Master of Biomedical Science, Honours
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Harnessing the lymph nodes to treat cancer metastasis
PhD/MPhil, Master of Biomedical Science, Honours
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Targeting stem-like T cell niches to treat chronic infections
PhD/MPhil, Master of Biomedical Science, Honours
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New ways of targeting monocytes to treat infection and cancer
PhD/MPhil, Master of Biomedical Science, Honours
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Neuroimmune interactions in virus infection
PhD/MPhil, Master of Biomedical Science
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Deep learning approaches to track immune cell migration in vivo
PhD/MPhil
Research degrees at the Doherty Institute are administered by the University of Melbourne.