The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Metagenomics for infectious diseases diagnostics and identifying antimicrobial resistance

Howden Group

Metagenomics (the sequencing of all genetic material in a sample) is an exciting new technology that can be applied to the diagnosis and characterisation of infectious diseases. Using state-of-the-art sequencing technology available in the MDU PHL, and with access to clinical samples from complex infectious diseases cases, this project will use this new technology to understand how it can be best applied to inform the management of patients with serious infections. Additionally, the technology will be applied to uncover the repertoire of antimicrobial resistance elements in clinical samples to improve the tracking and treatment of resistant pathogens. 

Contact project supervisor for further
information and application enquiries

Project Supervisor

Professor Ben Howden, Dr Jason Kwong

Project availability
Master of Biomedical Science

Howden Group

[email protected]

3 vacancies

Antimicrobial Resistance and Healthcare Associated Infections
Host Pathogens Interactions
Cross Cutting Disciplines
Global Health
Indigenous Health

Research Projects 2019 | 19 The Howden group is embedded in the state public health laboratory - the Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL) - with expertise in pathogen genomics and antimicrobial resistance, including functional genomics technologies and models of disease. We complement these molecular biology studies with epidemiological and clinical studies to address a broad range of issues related to invasive bacterial diseases in humans, especially those caused by staphylococci, enterococci and other antimicrobial-resistant species (CPE). Working closely with scientists in the MDU PHL, we investigate the epidemiology, evolution and spread of bacterial pathogens of public health significance such as Neisseria gonorrhoea, Listeria monocytogenes, Legionella spp. and Salmonella spp. 

Howden Group Current Projects