The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

EDUCATION

Research Projects

Project: Investigating the role of functional antibodies against Mycobacterium tuberculosis

Chung group

Mycobacterium tuberculosis (Mtb) infects approximately one third of the world’s population and is currently one of the major causes of morbidity and death worldwide. The role of antibodies in Mtb is underexplored, although rare studies suggest that antibodies may contribute to Mtb control. Preliminary studies by our lab suggest that patients that can control Mtb (latently infected) have improved functional antibody responses compared to symptomatic (active) Mtb patients. Therefore, we are interested in characterising the antibodies from patients with different clinical Mtb disease outcomes in order to further understand the importance of these potentially protective antibodies.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Dr Amy Chung

Project Co-supervisor

Professor Stephen Kent

Project availability
PhD/MPhil
Master of Biomedical Science

Chung group

[email protected]

3 vacancies

Themes
Immunology
Viral Infectious Diseases
Cross Cutting Disciplines
Discovery Research

The Chung group has an interest in understanding how an antibody can instruct the innate immune system to attack and protect against a range of infectious diseases including HIV, Mycobacterium tuberculosis and malaria through engagement with their Fc regions. Ultimately, our research aims to understand the mechanisms behind these antibodies in order to guide the development of more effective antibody therapeutics and vaccines.


Chung group Current Projects