Project: Innate-help for T cell priming
Beattie Group
We have discovered a unique function for innate and innate-like T cells in the early activation of dendritic cells in immune priming, through production of the cytokine Interleukin-4. We are now assessing how this effects dendritic cell function through a combination of techniques including in vivo imaging, RNA sequencing and CRISPR based gene knockdown. The broad spectrum effect of IL-4 will have implications across infectious disease, vaccination and possibly immunotherapy for diseases such as cancer.
Contact project supervisor for further
information and application enquiries
Beattie Group
3 vacancies
Dr Beattie works closely with the Heath laboratory to investigate fundamental immunological questions around optimal priming for the generation of effective and long-lived immune responses to pathogens, including malaria.
Beattie Group Current Projects
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Innate-help for T cell priming
PhD/MPhil, Master of Biomedical Science, Honours
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What makes long-lived memories?
PhD/MPhil, Master of Biomedical Science, Honours
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New ways to see inside the spleen - 3-photon, live imaging of T cell activation
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.