Project: Improving responses to antimicrobial-resistant Niesseria gonorrohoea with the use of genomics and novel infection modelling
The incidence of sexually transmitted infections (STIs), such as Neisseria gonorrhoeae is rising in both developed and developing regions of the world. Antimicrobial resistance (AMR) compromises current STI diagnostic and treatment strategies and as such, there is a need for new approaches to combat AMR STIs. In this project, we will apply metagenomic approaches to the rapid detection of AMR directly from clinical specimens, using a combination of both short and long-read sequencing. These strains will also be characterised in a novel cell culture model. Together, the findings of this project may contribute to understanding host-pathogen interactions of Neisseria gonorrhoeae. Diagnostic approaches employed will improve responses to STIs, aiding in the prevention of AMR development and spread, and improving patient outcomes.
Pasricha Group Current Projects
Improving responses to antimicrobial-resistant Niesseria gonorrohoea with the use of genomics and novel infection modelling
PhD/MPhil, Master of Biomedical Science, Honours