Project: Immune responses to the human gastric pathogen Helicobacter pylori
Liaskos Group
Helicobacter pylori is a Gram negative bacterium that infects more than 3 billion people worldwide, causing a spectrum of diseases ranging from gastritis, to gastric ulcers and gastric cancer. H. pylori manipulates the host’s immune system into mounting an ineffective, chronic and mildly inflammatory immune response, to promote lifelong infection of the host. The exact mechanism(s) whereby H. pylori manipulates the host immune system to facilitate chronic H. pylori colonisation remain unknown. This project will examine the mechanisms whereby H. pylori and their products manipulates the human immune system to promote pathogenesis. This project involves a variety of microbiology, immunology and imaging based techniques.
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Liaskos Group
2 vacancies
The Liaskos group is primarily focused on understanding the cellular and molecular mechanisms of host-pathogen interactions, with particular focus on bacterial pathogens and bacterial membrane vesicles. We use a range of microbiology and immunology-based techniques to examine how bacterial pathogens that infect humans cause disease, and how the host detects and responds to these pathogens and their products.
Liaskos Group Current Projects
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Immune responses to the human gastric pathogen Helicobacter pylori
PhD/MPhil, Master of Biomedical Science, Honours
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Bacterial membrane vesicles and their role in promoting pathogenesis
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.