The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Host-pathogen interactions of influenza B viruses

Kent group

Influenza A and B viruses circulate annually during seasonal epidemics. Although influenza B viruses have a significant clinical and socio-economic impact, they have been overlooked compared to influenza A viruses. This project with utilise a combination of virology, molecular biology and reverse genetics techniques to understand the virus-host interactions of IBV in in vitro and in vivo models of infection. This project will allow a greater understanding of IBV evolution in humans.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Professor Stephen Kent

Project Co-supervisor

Dr Marios Koutsakos

Project availability

Kent group

7 vacancies

Cross Cutting Disciplines

Research Projects 2019 | 25 The Kent group has an interest in understanding how the immune response can be harnessed in the control of infectious pathogens including HIV, Mycobacterium tuberculosis and influenza. This includes understanding non-conventional T cells and how they are impacted by HIV infection despite the fact that they are not target cells for HIV replication. We use animal models to investigate ways to manipulate these cells and to understand how they are regulated during viral infection. We also examine how antibodies can instruct the innate immune system to attack invading pathogens through their Fc regions. Our research aims to understand the mechanisms behind these antibodies in order to guide the development of more effective antibody therapeutics and vaccines.