The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

EDUCATION

Research Projects

Project: Exploring changing infection dynamics: invasive non-typhoidal Salmonella enterica

Howden Group

Non-typhoidal Salmonella (NTS) is one of the leading causative agents for foodborne, gastrointestinal disease. There has been an increase in NTS associated with causing invasive disease, specifically bacteraemia, in human hosts. However, the host/pathogen interactions of these invasive NTS are poorly understood. This project will integrate pathogen genomics, microscopy and cellular microbiology to identify and characterise novel virulence-associated elements in NTS.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Dr Danielle Ingle

Project Co-supervisor

Associate Professor Hayley Newton
Professor Ben Howden

Project availability
PhD/MPhil
Honours

Howden Group

danielle.ingle@unimelb.edu.au

3 vacancies

Themes
Antimicrobial Resistance and Healthcare Associated Infections
Host Pathogens Interactions
Cross Cutting Disciplines
Epidemiology
Global Health
Indigenous Health

Research Projects 2019 | 19 The Howden group is embedded in the state public health laboratory - the Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL) - with expertise in pathogen genomics and antimicrobial resistance, including functional genomics technologies and models of disease. We complement these molecular biology studies with epidemiological and clinical studies to address a broad range of issues related to invasive bacterial diseases in humans, especially those caused by staphylococci, enterococci and other antimicrobial-resistant species (CPE). Working closely with scientists in the MDU PHL, we investigate the epidemiology, evolution and spread of bacterial pathogens of public health significance such as Neisseria gonorrhoea, Listeria monocytogenes, Legionella spp. and Salmonella spp.