Project: Exploring changing infection dynamics: invasive non-typhoidal Salmonella enterica
Howden Group
Non-typhoidal Salmonella (NTS) is one of the leading causative agents for foodborne, gastrointestinal disease. There has been an increase in NTS associated with causing invasive disease, specifically bacteraemia, in human hosts. However, the host/pathogen interactions of these invasive NTS are poorly understood. This project will integrate pathogen genomics, microscopy and cellular microbiology to identify and characterise novel virulence-associated elements in NTS.
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Howden Group
3 vacancies

Research Projects 2019 | 19 The Howden group is embedded in the state public health laboratory - the Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL) - with expertise in pathogen genomics and antimicrobial resistance, including functional genomics technologies and models of disease. We complement these molecular biology studies with epidemiological and clinical studies to address a broad range of issues related to invasive bacterial diseases in humans, especially those caused by staphylococci, enterococci and other antimicrobial-resistant species (CPE). Working closely with scientists in the MDU PHL, we investigate the epidemiology, evolution and spread of bacterial pathogens of public health significance such as Neisseria gonorrhoea, Listeria monocytogenes, Legionella spp. and Salmonella spp.
Howden Group Current Projects
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Exploring changing infection dynamics: invasive non-typhoidal Salmonella enterica
PhD/MPhil, Honours
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Towards precision biotherapeutics for combating multidrug resistance superbugs
PhD/MPhil, Master of Biomedical Science
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Phylodynamic modelling of outbreaks of multidrug resistant enteric pathogens
PhD/MPhil, Master of Biomedical Science, Honours
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Understanding the impact of Staphylococcus aureus evolution on severe infections
Master of Biomedical Science, Honours
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Defining how antibiotic use leads to the emergence of untreatable hospital superbugs
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Precision genomics for antimicrobial-resistant bacterial pathogens
Master of Biomedical Science, Honours