Project: Development and optimisation of methods for direct-sample capture of bacterial pathogens for long-read sequencing
Coin Group
This project focuses pathogen detection and characterisation by developing and optimising methods for direct-sample capture of bacterial pathogens. By eliminating the need for culture and isolation steps, this approach aims to streamline and accelerate the identification of bacterial pathogens from complex samples. Through the integration of innovative molecular techniques and state-of-the-art sequencing technologies, we aim to enhance the accuracy and efficiency of pathogen detection, contributing to the development of more effective diagnostic and surveillance strategies.
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Coin Group
3 vacancies
The Coin group applies genomic sequencing to characterise and understand the dynamics of human and bacterial genomics and transcriptomics. We utilise long-read, real-time sequencing for detection and characterization of bacterial pathogens direct from samples, and are leaders in the development of host immune response biomarkers for detection of bacterial and viral infections.We develop and use algorithmic approaches for analysis of high throughput sequence data.
Coin Group Current Projects
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Understanding the transcriptomic dynamics that govern the infective process of Mycobacterium tuberculosis
PhD/MPhil
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Development and optimisation of methods for direct-sample capture of bacterial pathogens for long-read sequencing
PhD/MPhil
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Bacterial pan-genome graphs for variant discovery and RNAseq for drug resistance prediction
PhD/MPhil
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Developing Generative Artificial Intelligence for designing RNA
PhD/MPhil, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.