The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital


Research Projects

Project: Developing germinal centre organoids for antibody maturation

Juno Group

In this project, we will develop in vitro germinal centre organoids that allow B cells to produce high quality antibodies against viral glycoproteins. Using human or mouse B cells and T cells, we will test different approaches to (cell culture, nanogels, etc) to form lymph node-like organoids that can be vaccinated against antigens including influenza and coronaviruses 

Contact project supervisor for further
information and application enquiries

Project Supervisor

Dr Jennifer Juno

Project Co-supervisor

Dr Wen Shi Lee

Project availability

Juno Group

0 vacancies

Viral Infectious Diseases
Cross Cutting Disciplines
Discovery Research

The Juno group is interested in the biogenesis of CD4 T follicular helper cells and their capacity to promote high quality antibody responses following infection or vaccination. Our major focus is immunity to viral infections such as influenza, SARS-CoV-2 and HIV. The lab uses a combination of human clinical samples and pre-clinical animal models to understand the phenotypic and functional characteristics of diverse CD4 T cell populations.