The Univeristy of Melbourne The Royal Melbourne Hopspital

A joint venture between The University of Melbourne and The Royal Melbourne Hospital

EDUCATION

Research Projects

Project: Breaking bacterial antibiotic resistance using ionobiotics

McDevitt group

Antibiotic-resistant pathogens represent an imminent global threat to health in the 21st century. The combination of rising rates of bacterial drug resistance and a waning antibiotic development pipeline requires that new approaches be developed to address this imminent healthcare crisis. This project will investigate the use of novel metal ion shuttling compounds (ionobiotics) to break drug resistance in high priority bacterial pathogens and render them susceptible to antibiotic treatment. This approach has the potential to restore the efficacy of our existing antibiotic arsenal.

Contact project supervisor for further
information and application enquiries

Project Supervisor

Professor Christopher McDevitt

Project Co-supervisor

Dr Stephanie Neville
Dr Aimee Tan

Project availability
PhD/MPhil
Honours

McDevitt group

christopher.mcdevitt@unimelb.edu.au

2 vacancies

Themes
Antimicrobial Resistance and Healthcare Associated Infections
Host Pathogens Interactions
Cross Cutting Disciplines
Discovery Research

Research in the McDevitt group seeks to understand how bacterial pathogens acquire and use metal ions and how this shapes the host-pathogen interaction during infection.