Project: Bacterial subversion strategies to resist host-mediated copper stress
McDevitt group
Copper is an essential metal in mammals, but is not used by any known process in the major human pathogen Streptococcus pneumoniae. During infection, S. pneumoniae is exposed to high levels of copper and has evolved a number of unique pathways to tolerate and subvert this host-mediated chemical stress. This project will investigate the previously uncharacterised subversion strategies employed by S. pneumoniae to resist copper stress and cause infection.
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information and application enquiries
McDevitt group
4 vacancies
Research in the McDevitt group seeks to understand how bacterial pathogens acquire and use metal ions and how this shapes the host-pathogen interaction during infection.
McDevitt group Current Projects
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Defining the metal ion homeostatic pathways of Klebsiella pneumoniae
PhD/MPhil, Honours
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Breaking bacterial antibiotic resistance using ionobiotics
PhD/MPhil, Master of Biomedical Science, Honours
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Bacterial subversion strategies to resist host-mediated copper stress
PhD/MPhil, Honours
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Targeting Klebsiella pneumoniae virulence by exploiting weaknesses in metal ion homeostasis
PhD/MPhil, Master of Biomedical Science, Honours
Research degrees at the Doherty Institute are administered by the University of Melbourne.