Project: Antigen and cellular dynamics of influenza infection
This project uses recombinant influenza viruses that deliver reporter molecules to track the antigen and immune cell dynamics of influenza infection in mice. We are interested in understanding which cells are being infected, where they traffick and how viral antigens get to draining lymphoid organs after infection.
The Wheatley group is interested in factors that program broad and durable humoural immunity against infectious pathogens such as SARS-CoV2 and influenza. Our research involves immunological charactersiaton of B cells and antibodies, development of assays and tools to study antiviral immunity, novel vaccine design and the development of monoclonal antibodies to treat or prevent infections.